Author's response to reviews Title:MiR-378 is an independent prognostic factor and inhibits cell growth and invasion in colorectal cancer Authors:

miR-506 inhibits cell proliferation and invasion by targeting TET family in colorectal cancer

Objective(s): Ten-eleven translocation (TET) family members have been shown to be involved in the development of many tumors. However, the biological role of the TET family and its mechanism of action in colorectal carcinogenesis and progression remain poorly understood. Materials and Methods:We measured the expression levels of TET family members in colorectal cancer (CRC) specimens, in the c...

Role of crocin in several cancer cell lines: An updated review

Cancer is a major public health problem worldwide. The most important considerable features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and immortality. Crocin, as a bioactive compound of saffron and as a water-soluble carotenoid has radical scavenging, anti-hyperlipidemia, memory improving, and inhibition of tumor growth effects. The present review was designe...

Author's response to reviews Title: CD133 expression is not an independent prognostic factor in stage II and III colorectal cancer but may predict the better outcome in patients with adjuvant therapy Authors:

The Effects of NDRG2 Overexpression on Cell Proliferation and Invasiveness of SW48 Colorectal Cancer Cell Line

Background: Colorectal cancer (CRC) is one of the most common causes of cancer-related death in the world. The expression of N-myc downstream-regulated gene 2 (NDRG2) is down-regulated in CRC. The aim of this study was to investigate the effect of NDRG2 overexpression on cell proliferation and invasive potential of SW48 cells.Methods: SW48 cells were transfected with a plasmid overexpressing ND...

Author's response to reviews Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Title: Capan-1 pancreatic cancer cells Authors:

Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Title: Capan-1 pancreatic cancer cells Authors: Andrew J Shirk ([email protected]) Rahul Kuver ([email protected]) 4 24 March 2005 Version: Date: Author's response to reviews: Please see the cover letter provided with the previously submitted revision of this manuscript regarding the resp...